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• Binding: Paperback

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[U567.Ebook] Download PDF Modern Prometheus: Editing the Human Genome with Crispr-Cas9, by James Kozubek

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Would you change your genes if you could? As we confront the 'industrial revolution of the genome', the recent discoveries of Crispr-Cas9 technologies are offering, for the first time, cheap and effective methods for editing the human genome. This opens up startling new opportunities as well as significant ethical uncertainty. Tracing events across a fifty-year period, from the first gene splicing techniques to the present day, this is the story of gene editing - the science, the impact and the potential. Kozubek weaves together the fascinating stories of many of the scientists involved in the development of gene editing technology. Along the way, he demystifies how the technology really works and provides vivid and thought-provoking reflections on the continuing ethical debate. Ultimately, Kozubek places the debate in its historical and scientific context to consider both what drives scientific discovery and the implications of the 'commodification' of life.

• Sales Rank: #102694 in Books
• Published on: 2016-10-18
• Original language: English
• Dimensions: 9.38" h x 1.05" w x 6.45" l, .0 pounds
• Binding: Hardcover
• 395 pages

Review
"A solid introduction to the current state of affairs." (Science) "A truly remarkable job of getting the nuances right, while dodging through the minefields between enthusiasm and easy dismissal." (George Church, Harvard)"A wonderful, rewarding and easily read book." (David Baltimore, winner of the Nobel Prize in Physiology or Medicine)"usefully pushes the discussion beyond obvious designer-baby concerns to the technique's limitations, and its broader implications for agriculture and the commercialization of science." (Nature) 

About the Author
James Kozubek is a staff scientist at the Brigham and Women's Hospital with affiliation to the Broad Institute of Harvard University and the Massachusetts Institute of Technology. Kozubek is also an established journalist whose science writing has appeared in The Boston Globe, The Atlantic and Scientific American, amongst others.

Most helpful customer reviews

7 of 7 people found the following review helpful.
A comprehensive, up-to-date look at genetic modification
By Steve G
I enjoyed this book because it is an up-to-date look at genetic modification. It explains all the major methods including zinc finger technology, TALENS and CRISPR-Cas9. However, a prior knowledge of biology is required to understand a lot of what author Jim Kozubek discusses. His discussions are comprehensive and he gets a lot of his materials through interviews. This is very interesting but some of the quotes are so long I forgot who he was interviewing. Sometimes he goes into too much detail and I would see the trees, not the forest. Kozubek also takes several detours that detract from the book. His discussion of Chomsky was incomprehensible and his discussion of Mary Shelley was interesting but largely irrelevant. His dives into philosophy were equally unappealing. However his discussions of the potential for gene editing and the ethical and legal implications were very good. Overall, despite the faults, I can recommend this book to anyone with a background in biology who wants to learn more about the subject.
Disclosure: I received this book free via Netgalley in exchange for an honest review.

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[W640.Ebook] PDF Ebook Making Mechanical Marvels In Wood, by Raymond Levy

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Are you fascinated by the moving mechanics often hidden from the eye in engines and machines?

After retiring from a long career in scientific machinery design, author Raymond Levy found a renewed interest in the construction and mechanics of basic wooden apparatuses. Making Mechanical Marvels in Wood is Levy's fascinating collection of DIY wooden mechanical projects. It demonstrates how you can use wood to construct a number of intriguing mechanisms that whiz and whir, bob and flip.

Choose from a variety of projects that are inspired by classic devices of the eighteenth and nineteenth centuries, including:

• The "Eccentric" of a conventional crankshaft
• The "Geneva Wheel" found in high-quality spring-wound watches
• The "Fast-Return Actuator" that is commonplace in many machine tools

While most other mechanical projects hide the movements inside, these projects are designed to perform their mechanical stunts with marbles that move, wheels that spin, and even pistons that pump to the delight of the folks who crank the handles.

With step-by-step instructions, scores of how-to illustrations, and draftsman-quality drawings, these wooden models are marvelously easy to make and enjoy.

• Sales Rank: #532165 in Books
• Published on: 2014-11-21
• Original language: English
• Number of items: 1
• Dimensions: 11.02" h x .44" w x 8.50" l, 1.10 pounds
• Binding: Paperback
• 210 pages

Most helpful customer reviews

33 of 34 people found the following review helpful.
A book filled with plans for small hands-on wooden machines
By Jim Barstow
This is a book filled with projects for machines that are fun to play with. Over the years I have built more than half of them. (And given them all away as Christmas presents.) The machines are unique and really fun to watch work. A relatively high level of woodworking skill is required.

30 of 32 people found the following review helpful.
a wonderful gift for the woodworker
By A Customer
I ordered this book for my dad last Christmas, and he has used all of the patterns at least once. He is constantly telling me how well-planned the book is. I'm not a woodworker, but my dad is, and he rates this book top notch!

16 of 17 people found the following review helpful.
excellent patterns for great models
By Artephius (.
I bought this book back in 1991 when it was new......and it set on my shelf for 17 years. In 2008, I made my first model...the wooden u-joint model. In the last few months I have made 6 more models. I have only had minor problems with a couple of patterns. The back plate patterns on a couple of models are very hard to follow...because he advocates making a jig......which is ok......except his jig is not the same size as the back plate......a minor issue.

I would rate myself an advanced woodworker with a full shop of tools.......and would rate these patterns challenging....but fun. My fellow engineers at work love playing with my finished models. They also would make great presents for the grand children.

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Through individual stories, essays, poetry, and critical analyses, Experiencing Race, Class, and Gender in the United States, Sixth Edition, introduces issues of race, class, and gender within an interdisciplinary framework. Themes of identity, power, and change are examined from many different perspectives and voices. Unlike most texts that focus on minorities victimized by discrimination, this anthology includes the experiences of the privileged and of those who resist change, and reinforces students’ understanding that they can effect changes in their lives and in society.

• Sales Rank: #160623 in Books
• Brand: Brand: McGraw-Hill Humanities/Social Sciences/Languages
• Published on: 2012-09-13
• Original language: English
• Number of items: 1
• Dimensions: 9.10" h x .80" w x 7.50" l, 1.55 pounds
• Binding: Paperback
• 480 pages

Features

• Used Book in Good Condition

Most helpful customer reviews

0 of 0 people found the following review helpful.
Loved It!
By Ames
We used this text for my Cultural Diversity course and I decided to keep it when the course ended. The articles are brief, interesting, and to the point. I found the one by Michael Moore really gave insight to his documentary experiences and why his life went the way that it did. I would have liked to see some information on weight discrimination, but this book really does what it should and makes some very important points.

0 of 0 people found the following review helpful.
Good
By Amir Mom
Used it for diversity class. Good book

0 of 0 people found the following review helpful.
Typically class book
By Adam G.
This was a good book and I used it for a college course. The book condition was good but there was some writing in the books from a previous student.

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